Commodore 65 prototype sells for $7,625

Did you adore your 64? Well, wanna buy a 65? That'll cost you.

Earlier this month we saw how fans of vintage home computers can get a little crazy on eBay, bidding up the price of a 1983 10MHz Texas Instruments TI-99/8 to $3,240.

Well that's nothing compared with the enthusiasm that Commodore commands. A prototype Commodore 65 more than doubled the winning TI bid when it sold on eBay recently for a whopping $7,625.

Described as by the seller as "the proposed successor to the most popular computer of all time," the C65 is a prototype engineering unit that's missing some chips. It doesn't even work, but it came with a prototype Mitsumi keyboard.

Regardless, bidders sure wanted to get their hands on it.

Developed around 1991, the 3.54MHz Commodore 65 was designed to build on the C64's success and, like the Commodore 128, be generally compatible with its software.

The 8-bit C65 had improved graphics, a built-in 3.5-inch floppy drive, up to 8MB of RAM, and 128K ROM. It ran Commodore BASIC 10.0.

Unfortunately the C65 project was cancelled before it got to market, and Commodore declared bankruptcy in 1994.

However, some C65s were made as engineering prototypes and survived the company's liquidation. The number of extant units is unknown; estimates range from dozens to hundreds.

The machine's MRSP was only $300-$350, according to this C65 page.

"A working 65 is the Holy Grail of the Commodore 8-bit world these days," the site says.

Until the Grail turns up, I'll just keep watching C64 ads.

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Are Honeybees Losing Their Way?

A single honeybee visits hundreds, sometimes thousands, of flowers a day in search of nectar and pollen. Then it must find its way back to the hive, navigating distances up to five miles (eight kilometers), and perform a "waggle dance" to tell the other bees where the flowers are.

A new study shows that long-term exposure to a combination of certain pesticides might impair the bee's ability to carry out its pollen mission.

"Any impairment in their ability to do this could have a strong effect on their survival," said Geraldine Wright, a neuroscientist at Newcastle University in England and co-author of a new study posted online February 7, 2013, in the Journal of Experimental Biology.

Wright's study adds to the growing body of research that shows that the honeybee's ability to thrive is being threatened. Scientists are still researching how pesticides may be contributing to colony collapse disorder (CCD), a rapid die-off seen in millions of honeybees throughout the world since 2006.

"Pesticides are very likely to be involved in CCD and also in the loss of other types of pollinators," Wright said. (See the diversity of pollinating creatures in a photo gallery from National Geographic magazine.)

Bees depend on what's called "scent memory" to find flowers teeming with nectar and pollen. Their ability to rapidly learn, remember, and communicate with each other has made them highly efficient foragers, using the waggle dance to educate others about the site of the food source.

Watch as National Geographic explains the waggle dance.

Their pollination of plants is responsible for the existence of nearly a third of the food we eat and has a similar impact on wildlife food supplies.

Previous studies have shown certain types of pesticides affect a bee's learning and memory. Wright's team wanted to investigate if the combination of different pesticides had an even greater effect on the learning and memory of honeybees.

"Honeybees learn to associate floral colors and scents with the quality of food rewards," Wright explained. "The pesticides affect the neurons involved in these behaviors. These [affected] bees are likely to have difficulty communicating with other members of the colony."

The experiment used a classic procedure with a daunting name: olfactory conditioning of the proboscis extension reflex. In layman's terms, the bee sticks out its tongue in response to odor and food rewards.

For the experiment, bees were collected from the colony entrance, placed in glass vials, and then transferred into plastic sandwich boxes. For three days the bees were fed a sucrose solution laced with sublethal doses of pesticides. The team measured short-term and long-term memory at 10-minute and 24-hour intervals respectively. (Watch of a video of a similar type of bee experiment.)

This study is the first to show that when pesticides are combined, the impact on bees is far worse than exposure to just one pesticide. "This is particularly important because one of the pesticides we used, coumaphos, is a 'medicine' used to treat Varroa mites [pests that have been implicated in CCD] in honeybee colonies throughout the world," Wright said.

The pesticide, in addition to killing the mites, might also be making honeybees more vulnerable to poisoning and effects from other pesticides.

Stephen Buchmann of the Pollinator Partnership, who was not part of Wright's study, underscored how critical pollinators are for the world. "The main threat to pollinators is habitat destruction and alteration. We're rapidly losing pollinator habitats, natural areas, and food—producing agricultural lands that are essential for our survival and well being. Along with habitat destruction, insecticides weaken pollinators and other beneficial insects."

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Ship Stranded: Love Boat to Horror Honeymoon

A Texas couple's fantasy wedding quickly turned into a nightmare honeymoon when the fire-damaged Carnival Cruise ship carrying them became stranded in the Gulf of Mexico.

Rob Mowlam, 37, and Stephanie Stevenson, 27, of Nederland, Texas, got married on the Carnival Triumph on Saturday. The four-day cruise was meant to be back to shore on Monday, but was left disabled by an engine fire on Sunday.

The ship is being slowly towed to shore and is expected to dock in Mobile, Ala., on Thursday if weather permits. The vessel is without air conditioning, many working toilets and some restaurant service. Passengers, many who are sleeping in tents on deck, have told ABC News the smell on the ship is foul.

That is the honeymoon setting for Mowlam and Stevenson.

"[Rob Mowlam] had been with his girlfriend, or fiance, for a long period of time and they just took the next step," Mowlam's brother James Mowlam III told ABCNews.com. "The captain is the king of the world when they're on the boat and he hitched them up."

James Mowlam said he was shocked when he heard about the stranded boat and the increasingly dire conditions on the ship.

"It is an atrocious scene to be subjected to," he said.

Mowlam said he has not been able to communicate with his brother, but that his father has had sporadic communication with him.

"It would be my guess that this would probably not be on anyone's great list of memorable wedding experiences," Mowlam said with a laugh. "Although, my mom told him that she was hoping they had a memorable wedding and I think this would classify as a memorable wedding experience."

Lt. Cmdr. Paul McConnell/U.S. Coast Guard/AP Photo

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The bride's brother, Justin Davis, told ABCNews.com that his sister works for a doctor's office and the cruise was a gift from the doctor to the staff.

Davis has not been able to speak to Stevenson but said that her two young sons are being cared for by her mother. He said his sister is tough and he guesses she's probably not scared.

"She might be a little aggravated at the situation, but I'd say she's [probably] handling it really well," he said.

Others on the ship do not seem to be handling the situation so well.

Elderly and disabled passengers aboard the ship are struggling to cope with the worsening conditions, according to at least one passenger.

"Elderly and handicap are struggling, the smell is gross," passenger Ann Barlow text-messaged ABC News overnight. "Our room is leaking sewage."

The head of Carnival Cruise Lines said the British-U.S.-owned company was working hard to ensure the thousands of passengers stranded on the disabled ship were as comfortable as possible while the vessel was being towed to a port in Alabama.

"I need to apologize to our guests and to our families that have been affected by a very difficult situation," Carnival Cruise Lines president and CEO Gerry Cahill said at a news conference Tuesday evening.

It was the first time since a fire erupted in Triumph's engine room Sunday, knocking out its four engines, that a company representative had spoken publicly. The Triumph, with roughly 4,200 people on board, was left bobbing like a 100,000-ton cork for more than 24 hours. Giant sea-faring tugboats then hooked up to the ship and began towing the nearly 900-foot-long ship to land.

Carnival spokeswoman Joyce Oliva told The Associated Press Tuesday that a passenger with a pre-existing medical condition was taken off the ship as a precaution. Everyone else will likely have to weather conditions such as scarce running water, no air conditioning and long lines for food.

Back on land, passenger Barlow's 11-year-old twins told ABC News Tuesday they are worried as more passengers continue to talk about living with limited power and sanitation.

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Plants listen more closely to kin than strangers

It is not just humans that like a natter with their nearest and dearest – plants pay most attention to their closest relatives.

When an insect bites a leaf, many plants release volatile chemicals to prime their neighbours for attack. The defences this triggers vary – some plants respond by attracting predatory insects that eat the herbivores, others make themselves less tasty.

Now Richard Karban of the University of California, Davis, has shown that for the sagebrush, responses to these warning signals can vary with relatedness.

At the start of three growing seasons, Karban's team exposed different branches of the same plants to volatile chemicals. The substances came from relatives of the same species whose leaves had been clipped to trigger chemical release.

By the end of the seasons, herbivores had done less damage to the branches exposed to chemicals from close relatives than to those receiving signals from more distant relatives – the warning probably prompting the plants to release herbivore-deterring chemicals, says Karban.

He has previously shown that the blend of volatiles varies enormously between individuals – "so much so that big peaks in some individuals are undetectable in others", he says.

However, there is some similarity between family members. Karban thinks this variability is being exploited by the plants as a kind of family-specific signature, to prevent eavesdroppers from listening in and to give those that share the same genes a greater chance of survival.

Some plants are genetically more resistant to being eaten than others, so it makes sense that plants should care more about their kin's fate than that of the general population.

"It is very elegant work," says Susan Dudley from McMaster University in Ontario, Canada, who has shown that plants competing for space in a small pot are less aggressive if they are related to their neighbours.

She thinks this kind of kin-recognition is probably common among many plants.

Journal Reference: Proceedings of the Royal Society B, doi: 10.1098/rspb.2012.3062

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Pre-pregnancy folic acid linked to lower autism risk

WASHINGTON: Children born to women who started taking folic acid supplements four to eight weeks before pregnancy appear to be at a lower risk of autism, a study showed on Tuesday.

Pal Suren of the Norwegian Institute of Public Health and colleagues looked into the use of folic acid supplements before and during early pregnancy, and any impact on the later risk of various disorders on the autism spectrum.

"Our main finding was that maternal use of folic acid supplements around the time of conception was associated with a lower risk of autistic disorder," the authors wrote in the Journal of the American Medical Association.

The journal recalled that many countries recommend flour be enriched with folic acid to lower the risk of birth defects, and that women are often advised to take folic acid supplements before and during pregnancy.

Despite the practice, European and North American studies have found that many pregnant women take less folate in their diet than is necessary to prevent neural tube defects.

Suren's research appears to confirm that the advice to take folic acid supplements is well-founded.

The 85,176 Norwegian children who took part in the study were born between 2002 and 2008.

Among the sample, 270 children, or 0.32 percent, were diagnosed with autism spectrum disorders, and researchers found that there was an inverse association between folic acid use and subsequent autism risks.

About 1 in 88 children, or 1.14 percent, in the United States have been identified with an autism spectrum disorder, according to the US Centres for Disease Control and Prevention.

Mothers who took folic acid supplements in early pregnancy had a 40 percent lower risk of having children with autistic disorder compared with mothers who did not take folic acid, the researchers found.

Folic acid is found in naturally high levels in foods such as dark leafy greens, asparagus and broccoli, as well as citrus fruits.

- AFP/de

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BlueStacks brings a boat-load of Android apps to the Surface Pro

Thanks to BlueStacks, Angry Birds can officially be found on almost every Surface.

(Credit:
BlueStacks)

Hunting around the Windows store for your favorite apps can sometimes be a sad and demoralizing experience, particularly if you just dropped about a grand for that slick new Surface Pro from Microsoft.

Enter the startup BlueStacks on its multicolored digital steed prepared to liberate the Surface with its
Android app player, shouting "Freedom!" at the top of its lungs a la Mel Gibson in "Braveheart."

Actually, you can just download a version of the BlueStacks App Player optimized for the
Surface Pro that was just released today, but I do recommend at least donning a bit of blue war paint before clicking to make for a more memorable experience.

BlueStacks' app player is a sort of emulator that allows the whole universe of more than 750,000 Android apps (malware and all) to run on a PC. The Windows and Mac versions were first released last year, and the new
Windows 8/Surface Pro download greatly expands the options for users who previously might have shed a tear when perusing the less than 40,000 apps currently offered on Microsoft's official Windows app market.

According to a release from the company, BlueStacks is officially supported Windows 8 software, which is perhaps the most interesting part of the tale, especially given jabs at Redmond like this one from BlueStacks CEO Rosen Sharma in the statement:

The number of mobile apps being written overall is expanding exponentially and Microsoft has not added apps to the handful it has. Our goal is to get people more value out of their Surface Pro and Win8 devices.

BlueStacks has struck a handful of deals with PC and component makers like AMD, Asus and Lenovo and says that BlueStacks will come pre-loaded on millions of PCs in the future.

Forget about zombies, folks, from here on out, it looks like we'll have to look for Angry Birds around every corner and on every, uh...Surface.

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Where Will Pope Benedict XVI Retire?

Someone with a suspicious mind and deep knowledge of Vatican trivia might have guessed that something was going on months ago. Last November, a community of cloistered nuns vacated the  Mater Ecclesiae monastery, located inside Vatican Gardens, two years before they were expected to do so.

The monastery has since been closed for renovation.

On Monday, in the press conference that followed Pope Benedict XVI's announcement that he will resign at the end of the month, Father Federico Lombardi, director of the Holy See Press Office,  revealed that the monastery will be the retired pontiff's new home. (Photo Gallery: Inside the Vatican.)

"When renovation work on the monastery of cloistered nuns inside the Vatican is complete, the Holy Father will move there for a period of prayer and reflection," Lombardi said.

Until then, the pope will stay at the Apostolical Palace and the Pontifical Villas in Castel Gandolfo, a small lake town about 15 miles (24 kilometers) southeast of Rome, which serves as the traditional summer residence for popes.

The Mater Ecclesiae monastery was founded in 1992 by Benedict's predecessor, John Paul II, "to create a place to house an international convent for contemplative life within the walls of Vatican City," according to the Vatican City State website.

It has housed small communities of cloistered nuns whose main task has been to provide spiritual assistance to the pope and to the Roman Catholic Church as a whole by praying in Latin and singing Gregorian chants.

The nuns would also embroider papal garments and cultivate a small organic orchard and a rose garden next to their residence. In a 2009 interview with the Vatican newspaper L'Osservatore Romano, the monastery's then abbess said that Benedict particularly appreciated the special-recipe marmalade that the nuns would prepare out of the oranges and lemons they picked in the Vatican orchard.

It is not yet clear for how long the soon-to-be-former pope will stay at the monastery. Lombardi has said that Benedict will not participate in the March conclave that will elect his successor, stressing that there will be "no confusion or division arising from his resignation."

Lombardi also said that he wasn't sure of Benedict's future title-there are no canon law provisions or historical precedents regarding the statute, prerogatives, or titles for a retired pope.

Resignations of Popes Past

Only a handful of popes have willfully or forcefully resigned in the church's history, the last case going back to 1415, almost 600 years ago.

"It was Pope Gregory XII, who, in a very sacrificial gesture, offered to resign so that the Council of Constance could assume his power and appoint a new pope, and in so doing bring an end [to the] Great Western Schism," Donald Prudlo, associate professor of history at Jacksonville State University in Alabama, told Vatican Radio.

Italian and foreign commentators have been likening Benedict's choice to a famous case of papal abdication-that of Celestine V, who was elected in 1294 and left the Roman throne only five months later.

"At the end of the 13th century, a very holy hermit named Peter was elected as Pope Celestine V in order to break a deadlock in the conclave that had lasted nearly three years," Prudlo explained. "He was elected because of his personal holiness, sort of a unity candidate. And once he got there, being a hermit, not used to the ways of the Roman Curia, he found himself somewhat unsuited to the task."

So he resigned and lived as a hermit—or, some historians say, as a prisoner—in a castle belonging to his successor, Boniface VIII, before dying in 1296.

Celestine is widely recognized as the object of Dante Alighieri's scolding verses in his Divine Comedy. The former pope was proclaimed saint in 1313.

In 2009, Benedict XVI visited Celestine's tomb in L'Aquila (map) and left the pallium—a vestment that is the symbol of papal authority—on the grave. Now that gesture is being interpreted as a premonition of the choice he would eventually make.

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Wanted Ex-Cop Possibly in Shootout, Chase

Fugitive former cop Christopher Dorner has barricaded himself inside a mountain cabin near Big Bear, Calif., and exchanged gunfire with police who had pursued him after he broke into a home in the area, authorities said.

Two San Bernadino County Sheriff's deputies injured in the firefight and subsequently airlifted to a nearby hospital. The extent of their injuries is unknown.

Dozens of local, state and federal authorities are at the scene in the San Bernadino Mountains, surrounding the cabin and engaged in an intense standoff with Dorner, a former Navy marksman who swore to kill police and their family members in a manifesto discovered online last week.

Dorner is believed to have broken into another home nearby and taken two women hostage before stealing a car, police said. Officials say Dorner crashed the vehicle and fled on foot, where sheriff's deputies and state Fish and Game officers exchanged fire with him, before he barricaded himself in the cabin.

The two hostages, who were tied up by Dorner but later escaped, were evaluated by paramedics and were determined to be uninjured.

Police have sealed all roads going into the area and imposed a no-fly zone above the cabin, which is in a wooded area that has received several inches of snow in recent days.

Four Big Bear area schools were briefly placed on lockdown.

The San Bernardino County Sheriff's Department stopped all traffic leaving the area and thoroughly searched vehicles, as SWAT team and tactical units could be seen driving toward the cabin, their sirens blaring.

Los Angeles Police Department/AP Photo

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Authorities believer Dorner may be watching reports of the standoff and have asked media not to broadcast images of police surrounding the cabin.

"If he's watching this, the message... is: Enough is enough. It's time to turn yourself in. It's time to stop the bloodshed. It's time to let this event and let this incident be over," said Los Angeles Police spokesman Andy Smith, told reporters at a press conference.

Dorner faces capital murder charges that involve the killing of Riverside police officer Michael Crain, who was gunned down in an ambush last Thursday.

Since then a massive manhunt has been underway, focused primarily in the San Bernardino Mountains, but extending to neighboring states and as far away as Mexico.

A capital murder charge could result in the death penalty if Dorner is captured alive and convicted. Crain was married with two children, aged 10 and 4.

The charges do not involve the slayings of Monica Quan and her fiance, who were found shot to death Feb. 3. Quan was the daughter of former LAPD Capt. Randal Quan, who was mentioned as a target of Dorner's fury in his so-called "manifesto," which he posted on his Facebook page.

PHOTOS: Former LAPD Officer Suspected in Shootings

In the 6,000 word "manifesto," Dorner outlined his anger at the Los Angeles Police Department for firing him, and made threats against individuals he believed were responsible for ending his career with the police force five years ago.

Dorner's grievance with police goes back five years when he was fired after filing a false report accusing other cops of brutality.

The LAPD has assigned 50 protection details to guard officers and their families who were deemed possible targets.

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Arctic sunshine cranks up threat from greenhouse gases

IT'S a solar double whammy. Not only does sunlight melt Arctic ice, but it also speeds up the conversion of frozen organic matter into carbon dioxide.

The amount of carbon in dead vegetation preserved in the far northern permafrost is estimated to be twice what the atmosphere holds as CO₂. Global warming could allow this plant matter to decompose, releasing either CO₂ or methane – both greenhouse gases. The extent of the risk remains uncertain because the release mechanisms are not clear.

Rose Cory at the University of North Carolina at Chapel Hill and her colleagues analysed water from ponds forming on melting permafrost at 27 sites across the Arctic. They found that the amount of CO₂ released was 40 per cent higher when the water was exposed to ultraviolet light than when kept dark. This is because UV light, a component of sunlight, raises the respiration rate of soil bacteria and fungi, amplifying the amount of organic matter they break down and the amount of CO₂ released.

The thawing Arctic is emerging as a potentially major source of positive feedback that could accelerate global warming beyond existing projections. "Our task now is to quantify how fast this previously frozen carbon may be converted to CO₂, so that models can include the process," Cory says.

Journal reference: PNAS, DOI: 10.1073/pnas.1214104110.

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IBM puts supercomputer to work on cancer

WASHINGTON: IBM is putting its Watson supercomputer to work fighting cancer, in what is described as the first commercial program of its kind to use "big data" to help patients with the disease.

The US computing giant last week unveiled its initiative with health insurer WellPoint and Memorial Sloan-Kettering Cancer Center in New York.

The supercomputer, which gained fame by defeating two human champions in the "Jeopardy!" quiz show, has been sifting through some 600,000 pieces of medical evidence, two million pages of text from 42 medical journals and clinical trials in oncology research.

This can speed up the way data is analysed to make the best diagnosis and find the optimal treatment, says Craig Thompson, Sloan-Kettering's president.

"It can take years for the latest developments in oncology to reach all practice settings," Thompson said.

"The combination of transformational technologies found in Watson with our cancer analytics and decision-making process has the potential to revolutionise the accessibility of information for the treatment of cancer in communities across the country and around the world."

IBM first announced plans to work with WellPoint in 2011, and last year began receiving data from the New York research hospital which specialises in cancer.

The first application will work with 1,500 lung cancer cases, where clinicians and analysts are training Watson to extract and interpret physician notes, lab results and clinical research.

The Maine Center for Cancer Medicine and Westmed Medical Group will be two centres testing the service and providing feedback to WellPoint, IBM and Memorial Sloan-Kettering.

"IBM's work with WellPoint and Memorial Sloan-Kettering Cancer Center represents a landmark collaboration in how technology and evidence based medicine can transform the way in which health care is practiced," said Manoj Saxena at IBM.

"These breakthrough capabilities bring forward the first in a series of Watson-based technologies, which exemplifies the value of applying big data and analytics and cognitive computing to tackle the industry's most pressing challenges."

The program is being commercialised under the name Interactive Care Insights for Oncology, powered by Watson.

Watson, named after IBM founder Thomas Watson, can ingest tens of million pages of data in just seconds.

- AFP/jc

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